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This diagnostic test may be ordered if the doctor wants to symptoms of anal fissure out a more serious disease of the anus. American Journal of Gastroenterology. Anal fissure care at Mayo Clinic. The reduced blood flow prevents healing. It results symptoms of anal fissure a tear in the normally tough, fibrous, sheet-like wall between the rectum and vagina…. Anoscopy and sigmoidoscopy. Mayo Clinic Marketplace Check out these best-sellers and special offers on books and newsletters from Mayo Clinic.